A revived Hurricane Ian set its sights on South Carolina’s coast Friday and the historic city of Charleston, with forecasters predicting a storm surge and floods after the megastorm caused catastrophic damage in Florida and left people trapped in their homes.

With all of South Carolina’s coast under a hurricane warning, a steady stream of vehicles left Charleston on Thursday, many likely heeding officials’ warnings to seek higher ground. Storefronts were sandbagged to ward off high water levels in an area prone to inundation.

On Friday morning in Charleston, powerful wind gusts bent tree branches and sent sprays of steadily falling rain sideways. Streets in the 350-year-old city were largely empty, an ordinarily packed morning commute silenced by the advancing storm.

With winds holding at 85 mph (140 kph), the National Hurricane Center’s update at 8 a.m. Friday placed Ian about 105 miles (175 km) southeast of Charleston and forecast a “life-threatening storm surge” and hurricane conditions along the Carolina coastal area later Friday.

The hurricane warning stretched from the Savannah River to Cape Fear, with flooding likely across the Carolinas and southwestern Virginia, the center said. The forecast predicted a storm surge of up to 7 feet (2.1 meters) into coastal areas of the Carolinas, and rainfall of up to 8 inches (20 centimeters).

In Florida, rescue crews piloted boats and waded through riverine streets Thursday to save thousands of Floridians trapped amid flooded homes and buildings shattered by Hurricane Ian.

Florida Gov. Ron DeSantis said at least 700 rescues, mostly by air, were conducted on Thursday involving the U.S. Coast Guard, the National Guard and urban search-and-rescue teams.

Ian had come ashore Wednesday on Florida’s Gulf Coast as a monstrous Category 4 hurricane, one of the strongest storms ever to hit the U.S. It flooded homes on both the state’s coasts, cut off the only road access to a barrier island, destroyed a historic waterfront pier and knocked out electricity to 2.6 million Florida homes and businesses _ nearly a quarter of utility customers. Some 2.1 million of those customers remained in the dark days afterward.

Climate change added at least 10% more rain to Hurricane Ian, according to a study prepared immediately after the storm, said its co-author, Lawrence Berkeley National Lab climate scientist Michael Wehner.

At least six people were confirmed dead in Florida, including two who died Thursday afternoon when their car hydroplaned and overturned in a water-filled ditch in north Florida’s Putnam County, while three other people were reported killed in Cuba after the hurricane struck there on Tuesday.

In the Fort Myers area, the hurricane ripped homes from their slabs and deposited them among shredded wreckage. Businesses near the beach were completely razed, leaving twisted debris. Broken docks floated at odd angles beside damaged boats. Fires smoldered on lots where houses once stood.

“I don’t know how anyone could have survived in there,” William Goodison said amid the wreckage of a mobile home park in Fort Myers Beach where he’d lived for 11 years. Goodison said he was alive only because he rode out the storm at his son’s house inland.

The hurricane tore through the park of about 60 homes, leaving many destroyed or mangled beyond repair, including Goodison’s single-wide home. Wading through waist-deep water, Goodison and his son wheeled two trash cans containing what little he could salvage _ a portable air conditioner, some tools and a baseball bat.

The road into Fort Myers was littered with broken trees, boat trailers and other debris. Cars were left abandoned in the road, having stalled when the storm surge flooded their engines.

Lee County Sheriff Carmine Marceno said his office was scrambling to respond to thousands of 911 calls in the Fort Myers area, but many roads and bridges were impassable.

Emergency crews sawed through toppled trees to reach stranded people. Many in the hardest-hit areas were unable to call for help because of electrical and cellular outages.

A chunk of the Sanibel Causeway fell into the sea, cutting off access to the barrier island where 6,300 people live.

Hours after weakening to a tropical storm while crossing the Florida peninsula, Ian regained hurricane strength Thursday evening over the Atlantic. The National Hurricane Center predicted it would hit South Carolina as a Category 1 hurricane Friday.

National Guard troops were being positioned in South Carolina to help with the aftermath, including any water rescues. And in Washington, President Joe Biden approved an emergency declaration for the state, a needed step to speed federal assist for recovery once Ian passes.

The storm was on track to later hit North Carolina, forecasters said. North Carolina Gov. Roy Cooper urged residents to prepare for torrents of rain, high winds and potential power outages.

Visiting the state’s emergency operations center Thursday, Cooper said that up to 7 inches (17.8 centimeters) of rain could fall in some areas, with the potential for mountain landslides and tornadoes statewide.